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National screening campaigns for colorectal cancer should include
the general population, not just patients with a family history
of the disease, according to researchers in the United Kingdom.
Researchers
conducted a population study of more than 30,000 people, and said
that colorectal cancer in a close relative more than doubled the
risk of developing the disease. Those with a relative under 45
with colorectal cancer or with 2 relatives suffering from the
disease had up to 5 times the risk of developing colon cancer,
according to the study published in the Journal of Medical Screening.
But while
the risk of colon cancer is much greater among those with a family
history, approximately 85 percent of colorectal cancers develop
in people with no family history of the disease, the researchers
said.
"Based
on the prevalence estimates reported here, screening strategies
targeted solely at people with a family history will have limited
impact on reducing mortality from colorectal cancer at the population
level," concluded the researchers.
Other
sources: British Medical Association
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