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A researcher
at the Barbara Ann Karmanos Cancer Institute reports discovering
of a natural protein that may stop the spread of gastrointestinal
cancer.
Adhip Majumdar,
Ph.D. said he isolated a protein within the gene, ERRP (epidermal
growth factor receptor related protein), that appears to act as
the body's own defense against malignancy.
"We put the
gene in prostate and colon cancer cells and both (cancers) were
inhibited," Majumdar reported in the American Journal of Physiology
and the Journal of Anticancer Research.
By targeting
epithelial cancer cells, ERRP regulates and stops cancer cell
proliferation in the breast, colon and pancreas, reports Majumdar.
"If the protein
could be purified in large quantities, it could be used to prevent
and treat cancer," said Dr. Omer Kucuk, professor of hematology
and oncology at Wayne State. "Since it is our natural defense
against cancer, the use of this protein in humans may be less
toxic and more effective than the commercially available products
attempting to do the same."
Other
Sources: karmanos Cancer Institute
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