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Patients taking
Coumadin (warfarin) for anticoagulation therapy may undergo colonoscopy
screening for colorectal cancer without fear of hemorrhage, according
to researchers at the Ochsner Clinic Foundation in New Orleans.
However, hot
biopsy and snare procedures during the screeening slightly increase
the risk of hemorrhaging, according to the study published in
Diseases of the Colon and Rectum.
Researchers
analyzed 94 patients who underwent a colonoscopy who were taking
Coumadin for anticoagulation therapy. Patients were advised to
stop taking the drug three days before the colonoscopy procedure
and to restart the drug the day afterwards.
Forty-seven
patients underwent either a hot biopsy or snare polypectomy as
part of their screening. One patient who required several biopsies
had complications from hemorrhage requiring hospitalization and
transfusion, according to the researchers.
"Patients
taking warfarin for anticoagulation may safely undergo colonoscopy,"
said Dr. Stephania K. C. Timothy, co-author of the study. "The
risk of hemorrhagic complications increases slightly with hot
biopsy or snare procedures. Further studies are needed to refine
guidelines for colonoscopy in the patient requiring anticoagulation."
Other
Sources: Disease of the Colon and Rectum
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